The book “Textbook of Medical Biochemistry” provides precise and concise information on biochemistry with clinical approaches to understand the different disease processes. This edition of the book is updated with colour printing to make it more attractive, easy recording and also highlights the significant portions like clinical aspects and biochemistry importance. There are six sections and at the end of each chapter, multiple choice questions and essay type questions are provided. The first section deals with cell biology, where it explains about chemistry and functions of cells and cell organelles, structure of biological membranes and function of biological membranes. Chemistry of biomolecules is the second section. This section provides the user with immense knowledge on chemistry and function of carbohydrates, lipids, prostaglandins, plasma proteins, etc. The third section molecular biology discusses about chemistry of nucleotides, metabolism of purines and pyrimidines, protein synthesis, polymerase chain reaction, human genome project, gene therapy and biochemistry of cholera. The fourth section provides the information on metabolism. The fifth chapter on clinical biochemistry describes about enzymes and isoenzymes of clinical importance, renal function tests, liver function tests, gastric function tests, and many other tests. The last section provides knowledge on diet and nutrition, environmental biochemistry, biochemical techniques, biophysics, biochemistry of AIDS and biochemistry of ageing.